Vitalism and Synthesis of Urea

  title={Vitalism and Synthesis of Urea},
  author={E Kinne-saffran and Rolf K. H. Kinne},
  journal={American Journal of Nephrology},
  pages={290 - 294}
In 1828, Friedrich Wöhler, a German physician and chemist by training, published a paper that describes the formation of urea, known since 1773 to be a major component of mammalian urine, by combining cyanic acid and ammonium in vitro. In these experiments the synthesis of an organic compound from two inorganic molecules was achieved for the first time. These results weakened significantly the vitalistic hypothesis on the functioning of living cells, although Wöhler, at that time, was more… 

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