Vital staining for cell death identifies Atg9a-dependent necrosis in developmental bone formation in mouse

@inproceedings{Imagawa2016VitalSF,
  title={Vital staining for cell death identifies Atg9a-dependent necrosis in developmental bone formation in mouse},
  author={Yusuke Imagawa and Tatsuya Saitoh and Yoshihide Tsujimoto},
  booktitle={Nature communications},
  year={2016}
}
Programmed cell death has a crucial role in various biological events, including developmental morphogenesis. Recent evidence indicates that necrosis contributes to programmed cell death in addition to apoptosis, but it is unclear whether necrosis acts as a compensatory mechanism for failure of apoptosis or has an intrinsic role during development. In… CONTINUE READING