Visualizing the spindle checkpoint in Drosophila spermatocytes.

  title={Visualizing the spindle checkpoint in Drosophila spermatocytes.},
  author={Elena Rebollo and Cayetano Gonzalez},
  journal={EMBO reports},
  volume={1 1},
The spindle assembly checkpoint detects defects in spindle structure or in the alignment of the chromosomes on the metaphase plate and delays the onset of anaphase until defects are corrected. Thus far, the evidence regarding the presence of a spindle checkpoint during meiosis in male Drosophila has been indirect and contradictory. On the one hand, chromosomes without pairing partners do not prevent meiosis progression. On the other hand, some conserved components of the spindle checkpoint… CONTINUE READING
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