Visualizing the spatial gene expression organization in the brain through non-linear similarity embeddings.


The Allen Brain Atlases enable the study of spatially resolved, genome-wide gene expression patterns across the mammalian brain. Several explorative studies have applied linear dimensionality reduction methods such as Principal Component Analysis (PCA) and classical Multi-Dimensional Scaling (cMDS) to gain insight into the spatial organization of these… (More)
DOI: 10.1016/j.ymeth.2014.10.004


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