Visualizing the Neural Bases of a Disconnection Syndrome with Diffusion Tensor Imaging

@article{Molko2002VisualizingTN,
  title={Visualizing the Neural Bases of a Disconnection Syndrome with Diffusion Tensor Imaging},
  author={Nicolas Molko and Leslie G. Cohen and J. F. Mangin and Florence Chochon and S. Lehricy and Denis Le Bihan and Stanislas Dehaene},
  journal={Journal of Cognitive Neuroscience},
  year={2002},
  volume={14},
  pages={629-636}
}
Disconnection syndromes are often conceptualized exclusively within cognitive box-and-arrow diagrams unrelated to brain anatomy. In a patient with alexia in his left visual field resulting from a posterior callosal lesion, we illustrate how diffusion tensor imaging can reveal the anatomical bases of a disconnection syndrome by tracking the degeneration of neural pathways and relating it to impaired fMRI activations and behavior. Compared to controls, an abnormal pattern of brain activity was… CONTINUE READING
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