Visualizing spatial lipid distribution in porcine lens by MALDI imaging high-resolution mass spectrometry.

@article{Vidov2010VisualizingSL,
  title={Visualizing spatial lipid distribution in porcine lens by MALDI imaging high-resolution mass spectrometry.},
  author={Veronika Vidov{\'a} and Jaroslav P{\'o}l and Michael Voln{\'y} and Petr Nov{\'a}k and Vladim{\'i}r Havl{\'i}{\vc}ek and Susanne K Wiedmer and Juha Holopainen},
  journal={Journal of lipid research},
  year={2010},
  volume={51 8},
  pages={2295-302}
}
The intraocular lens contains high levels of both cholesterol and sphingolipids, which are believed to be functionally important for normal lens physiology. The aim of this study was to explore the spatial distribution of sphingolipids in the ocular lens using mass spectrometry imaging (MSI). Matrix-assisted laser desorption/ionization (MALDI) imaging with ultra high resolution Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) was used to visualize the lipid spatial… CONTINUE READING

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