Visualizing presynaptic function

@article{Kavalali2014VisualizingPF,
  title={Visualizing presynaptic function},
  author={Ege T Kavalali and Erik M. Jorgensen},
  journal={Nature Neuroscience},
  year={2014},
  volume={17},
  pages={10-16}
}
Synaptic communication in the nervous system is initiated by the fusion of synaptic vesicles with the presynaptic plasma membrane and subsequent neurotransmitter release. In the 1980s, this process was characterized by electron microscopy, albeit without the ability to follow processes in living cells. In the last two decades, fluorescence imaging methods have been developed that report synaptic vesicle fusion, endocytosis and recycling. These probes have provided unprecedented insight into… CONTINUE READING
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