Visualizing feasible operating ranges within tissue engineering systems using a "windows of operation" approach: a perfusion-scaffold bioreactor case study.

@article{McCoy2012VisualizingFO,
  title={Visualizing feasible operating ranges within tissue engineering systems using a "windows of operation" approach: a perfusion-scaffold bioreactor case study.},
  author={Ryan J. McCoy and Fergal J O'Brien},
  journal={Biotechnology and bioengineering},
  year={2012},
  volume={109 12},
  pages={
          3161-71
        }
}
Tissue engineering approaches to developing functional substitutes are often highly complex, multivariate systems where many aspects of the biomaterials, bio-regulatory factors or cell sources may be controlled in an effort to enhance tissue formation. Furthermore, success is based on multiple performance criteria reflecting both the quantity and quality of the tissue produced. Managing the trade-offs between different performance criteria is a challenge. A "windows of operation" tool that… CONTINUE READING
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