Visualizing drug efficacy in vivo.

  title={Visualizing drug efficacy in vivo.},
  author={Zhang Weisheng and Chen Rui Min and David B. West and Anthony F. Purchio},
  journal={Molecular imaging},
  volume={4 2},
Many enzymes are therapeutic targets for drug discovery, whereas other enzymes are important for understanding drug metabolism and pharmacokinetics during compound testing in animals. Testing of drug efficacy and metabolism in an animal model requires the measurement of disease endpoints as well as assays of enzyme activity in specific tissues at selected… CONTINUE READING