Visualizing dopamine transporter integrity with iodine-123-FP-CIT SPECT in combination with high resolution MRI in the brain of the common marmoset monkey

@article{GareaRodriguez2012VisualizingDT,
  title={Visualizing dopamine transporter integrity with iodine-123-FP-CIT SPECT in combination with high resolution MRI in the brain of the common marmoset monkey},
  author={Enrique Garea-Rodriguez and Christina Schlumbohm and Boldizs{\'a}r Cz{\'e}h and Jessica K{\"o}nig and Gunther Helms and C. J. Heckmann and Birgit Meller and Johannes Meller and Eberhard Fuchs},
  journal={Journal of Neuroscience Methods},
  year={2012},
  volume={210},
  pages={195-201}
}
Considerable progress has been made in small animal single photon emission computed tomography (SPECT) imaging in the field of Parkinson's disease. In preclinical research, there is an increasing demand for in vivo imaging techniques to apply to animal models. Here, we report the first protocol for dopamine transporter (DAT) SPECT in common marmosets using the radioligand ¹²³I-N-ω-fluoropropyl-2β-carbomethoxy-3β-{4-iodophenyl}nortropane (¹²³I-FP-CIT). Serial SPECT images were obtained on an… CONTINUE READING

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