Visualization of ultradeformable liposomes penetration pathways and their skin interaction by confocal laser scanning microscopy.

@article{Subongkot2013VisualizationOU,
  title={Visualization of ultradeformable liposomes penetration pathways and their skin interaction by confocal laser scanning microscopy.},
  author={Thirapit Subongkot and Nanthida Wonglertnirant and Pucharee Songprakhon and Theerasak Rojanarata and Praneet Opanasopit and Tanasait Ngawhirunpat},
  journal={International journal of pharmaceutics},
  year={2013},
  volume={441 1-2},
  pages={151-61}
}
The objective of this study was to elucidate the skin penetration pathway of the generated ultradeformable liposomes (ULs) with terpenes for transdermal drug delivery of fluorescein sodium (NaFl). ULs with d-limonene were selected to investigate the penetration pathways and vesicle-skin interaction in terms of release and attachment processes via Confocal Laser Scanning Microscopy (CLSM). A co-localization technique was employed to visualize the skin penetration behavior of UL-labeled red… CONTINUE READING
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