Visualization of tyrosinase activity in melanoma cells by a BODIPY-based fluorescent probe.

@article{Kim2011VisualizationOT,
  title={Visualization of tyrosinase activity in melanoma cells by a BODIPY-based fluorescent probe.},
  author={Tae-Il Kim and Jihye Park and Seonhwa Park and Yongdoo Choi and Youngmi Kim},
  journal={Chemical communications},
  year={2011},
  volume={47 47},
  pages={
          12640-2
        }
}
We have presented a fluorescent probe 1 that exhibits a fluorescence turn-on signal upon reaction with tyrosinase, and we show that it is readily employed for the assessment of tyrosinase activity and tyrosinase inhibitor activity in buffered aqueous solution, and further utilized for the visualization of endogenous tyrosinase activity in living melanoma cells. 
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TLDR
A fluorescent probe that exhibits a fluorescence turn-on signal upon reaction with tyrosinase is presented and it is shown that it can be readily employed for the assessment of tyros in buffered aqueous solution.
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