Visualization of ordered genomic RNA and localization of transcriptional complexes in rotavirus

@article{Prasad1996VisualizationOO,
  title={Visualization of ordered genomic RNA and localization of transcriptional complexes in rotavirus},
  author={B. V. Venkataram Prasad and Rosalba Rothnagel and Carl Q.-Y. Zeng and Joanita Jakana and Jeffrey A. Lawton and Wan-ling Chiu and Mary K. Estes},
  journal={Nature},
  year={1996},
  volume={382},
  pages={471-473}
}
Abstract IN double-stranded-RNA (dsRNA) viruses found in animals1, bacteria2 and yeast3, the genome is transcribed within the structurally intact core of the virion with extraordinary efficiency. The structural organization of the genome and the enzymes involved in the transcription inside any of these viruses, critical for understanding this process, is not known. Here we report what we believe is the first three-dimensional characterization of the viral genome and the transcription complex in… CONTINUE READING
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