Visualization of lymphatic vessels through NF-kappaB activity.

  title={Visualization of lymphatic vessels through NF-kappaB activity.},
  author={Marcia R Saban and Sylvie M{\'e}met and David M. Jackson and John Ash and Aurelio A Roig and Alain Isra{\"e}l and Ricardo Saban},
  volume={104 10},
The molecular biology of lymphatics is only rudimentary owing to the long-standing absence of specific markers, and scanty is the information regarding bladder lymphatic vessels. By using mice with a reporter gene for nuclear factor kappaB (NF-kappaB) activity (kappaB-lacZ) in combination with immunohistochemical staining with a specific lymphatic marker (LYVE-1), we show, for the first time, that NF-kappaB is constitutively active in lymphatic endothelium in the urinary bladder, uterus… CONTINUE READING


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