Visualization of human herpesvirus type 8 in Kaposi's sarcoma by light and transmission electron microscopy.

@article{Orenstein1997VisualizationOH,
  title={Visualization of human herpesvirus type 8 in Kaposi's sarcoma by light and transmission electron microscopy.},
  author={Jan Marc Orenstein and Serhan Alkan and Andrew Blauvelt and K T Jeang and Mark D Weinstein and Donald E Ganem and Brian G. Herndier},
  journal={AIDS},
  year={1997},
  volume={11 5},
  pages={F35-45}
}
BACKGROUND Human herpesvirus type 8 (HHV-8) has been associated with Kaposi's sarcoma, body cavity-based lymphoma (BCBL), and multicentric Castleman's disease through DNA, in situ hybridization, and serologic studies. HHV-8 has been visualized only in HHV-8-positive/Epstein-Barr virus (EBV)-negative/ cytomegalovirus (CMV)-negative BCBL cell lines, but not in HHV-8-positive/EBV-negative/ CMV-negative Kaposi's sarcoma lesions. DESIGN Kaposi's sarcoma of the skin, lymph node, and spleen from… CONTINUE READING

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