Visualization of antitumor treatment by means of fluorescence molecular tomography with an annexin V-Cy5.5 conjugate.

@article{Ntziachristos2004VisualizationOA,
  title={Visualization of antitumor treatment by means of fluorescence molecular tomography with an annexin V-Cy5.5 conjugate.},
  author={Vasilis Ntziachristos and Eyk A Schellenberger and Jorge Ripoll and Doreen Yessayan and Edward E Graves and Alexei Bogdanov and Lee Josephson and Ralph Weissleder},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2004},
  volume={101 33},
  pages={
          12294-9
        }
}
In vivo imaging of treatment responses at the molecular level could have a significant impact on the speed of drug discovery and ultimately lead to personalized medicine. Strong interest has been shown in developing quantitative fluorescence-based technologies with good molecular specificity and sensitivity for noninvasive 3D imaging through tissues and whole animals. We show herein that tumor response to chemotherapy can be accurately resolved by fluorescence molecular tomography (FMT) with a… CONTINUE READING

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