Visualising insulin secretion. The Minkowski Lecture 2004

  title={Visualising insulin secretion. The Minkowski Lecture 2004},
  author={Guy A Rutter},
Insulin secretion from pancreatic islet beta cells is a tightly regulated process, under the close control of blood glucose concentrations, neural inputs and circulating hormones. Defects in glucose-triggered insulin secretion, possibly exacerbated by a decrease in beta cell mass, are ultimately responsible for the development of type 2 diabetes. A full understanding of the mechanisms by which glucose and other nutrients trigger insulin secretion will probably be essential to allow for the… CONTINUE READING
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