Visualisation and Quantification of Intracellular Interactions of Neisseria meningitidis and Human α-actinin by Confocal Imaging

@inproceedings{Murillo2010VisualisationAQ,
  title={Visualisation and Quantification of Intracellular Interactions of Neisseria meningitidis and Human α-actinin by Confocal Imaging},
  author={Isabel Murillo and Mumtaz Virji},
  booktitle={Journal of visualized experiments : JoVE},
  year={2010}
}
The Opc protein of Neisseria meningitidis (Nm, meningococcus) is a surface-expressed integral outer membrane protein, which can act as an adhesin and an effective invasin for human epithelial and endothelial cells. We have identified endothelial surface-located integrins as major receptors for Opc, a process which requires Opc to first bind to integrin… CONTINUE READING