Visual acuity in the water maze: sensitivity to muscarinic receptor blockade in rats and mice

@article{Robinson2004VisualAI,
  title={Visual acuity in the water maze: sensitivity to muscarinic receptor blockade in rats and mice},
  author={Lianne Robinson and Dominic Harbaran and Gernot Riedel},
  journal={Behavioural Brain Research},
  year={2004},
  volume={151},
  pages={277-286}
}
A visual acuity task performed in the water maze in rats [Behav. Brain Res. 119 (2001) 77] was used to reveal the sensitivity of the visual system to muscarinic receptor blockade. Intraperitoneal injection of 0.2 mg/kg scopolamine had no effect, but 2 mg/kg severely compromised visual acuity, but did not affect the swim strategy to solve the task. Spatial learning in a reference memory version of the water maze, however, was impaired by 0.2 mg/kg scopolamine. It was also confirmed that the same… CONTINUE READING

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