Visual Pathway Mediating Pineal Response to Environmental Light

@article{Moore1967VisualPM,
  title={Visual Pathway Mediating Pineal Response to Environmental Light},
  author={R. Y. Moore and A. Heller and R. Wurtman and J. Axelrod},
  journal={Science},
  year={1967},
  volume={155},
  pages={220 - 223}
}
Activity of the melatoninforming enzyme, hydroxyindole-O-methyltransferase, in rat pineal is increased when the animal is exposed to continuous darkness, and it is decreased by exposure to continuous light. Response to environmental light is initiated in the retina and transmitted to the pineal by way of the central nervous system and the cervical sympathetics. The central visual pathway essential for mediation of this response is the inferior accessory optic tract. Visual pathways to thalamus… Expand
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In lower vertebrates an intracranial structure exists which contains typical photoreceptors and which responds to light falling on the surface of the head by an inhibition of neural activity. InExpand
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