Visual Map Development Depends On The Temporal Pattern of Binocular Activity in Mice

@inproceedings{Zhang2011VisualMD,
  title={Visual Map Development Depends On The Temporal Pattern of Binocular Activity in Mice},
  author={Jiayi Zhang and James B Ackman and Hong-ping Xu and Michael C. Crair},
  booktitle={Nature Neuroscience},
  year={2011}
}
Binocular competition is thought to drive eye-specific segregation in the developing visual system, potentially through Hebbian synaptic learning rules that are sensitive to correlations in afferent activity. Altering retinal activity can disrupt eye-specific segregation, but little is known about the temporal features of binocular activity that modulate visual map development. We used optogenetic techniques to directly manipulate retinal activity in vivo and identified a critical period before… CONTINUE READING