Visual DNA microarray for detection of epidermal growth factor receptor (EGFR) gene mutations.

Abstract

OBJECTIVE To develop a gold nanoparticle-based visual DNA microarray for simple and rapid screening of EGFR gene mutations. METHODS The DNA fragments contain epidermal growth factor receptor (EGFR) exons 18, 19, 20 and 21 were amplified by polymerase chain reaction (PCR) using biotin-modified primers. The amino-modified oligonucleotides were immobilized… (More)
DOI: 10.3109/00365513.2014.951680

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Cite this paper

@article{Xue2014VisualDM, title={Visual DNA microarray for detection of epidermal growth factor receptor (EGFR) gene mutations.}, author={Li Xue and Jing-Jing Fei and Yi Song and Rong-hua Xu and Yu-jie Bai}, journal={Scandinavian journal of clinical and laboratory investigation}, year={2014}, volume={74 8}, pages={693-9} }