Visfatin/pre-B-cell colony-enhancing factor (PBEF), a proinflammatory and cell motility-changing factor in rheumatoid arthritis.

@article{Meier2012VisfatinpreBcellCF,
  title={Visfatin/pre-B-cell colony-enhancing factor (PBEF), a proinflammatory and cell motility-changing factor in rheumatoid arthritis.},
  author={Florian Meier and Klaus W Frommer and Marvin A. Peters and Fabia Brentano and Stephanie Lef{\`e}vre and Dirk Schroeder and Diego Kyburz and Juergen Steinmeyer and Stefan Rehart and S. Kirsten Gay and Ulf Mueller-Ladner and Elena Neumann},
  journal={The Journal of biological chemistry},
  year={2012},
  volume={287 34},
  pages={28378-85}
}
Adipokines such as adiponectin and visfatin/pre-B-cell colony-enhancing factor (PBEF) have been recently shown to contribute to synovial inflammation in rheumatoid arthritis (RA). In this study, we evaluated the pathophysiological implication of visfatin/PBEF in the molecular patterns of RA synovial tissue, focusing on RA synovial fibroblasts (RASFs), key players in RA synovium. Expression of visfatin/PBEF in synovial fluid and tissue of RA patients was detected by immunoassays and… CONTINUE READING