Viscosity and drag force involved in organelle transport: investigation of the fluctuation dissipation theorem.

@article{Hayashi2013ViscosityAD,
  title={Viscosity and drag force involved in organelle transport: investigation of the fluctuation dissipation theorem.},
  author={Kumiko Hayashi and Chan Gi Pack and Masaaki K Sato and Kazunari Mouri and Kazo Kaizu and Kazutoshi Takahashi and Yasunori Okada},
  journal={The European physical journal. E, Soft matter},
  year={2013},
  volume={36 12},
  pages={136}
}
We observed the motion of an organelle transported by motor proteins in cells using fluorescence microscopy. Particularly, among organelles, the mitochondria in PC12 cells were studied. A mitochondrion was dragged at a constant speed for several seconds without pausing. We investigated the fluctuation dissipation theorem for this constant drag motion by comparing it with the motion of Brownian beads that were incorporated into the cells by an electroporation method. We estimated the viscosity… CONTINUE READING
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