Viscoelastic properties of red cell membrane in hereditary elliptocytosis.

@article{Chabanel1989ViscoelasticPO,
  title={Viscoelastic properties of red cell membrane in hereditary elliptocytosis.},
  author={A Chabanel and K. L. Paul Sung and J Rapiejko and Josef T Prchal and Jiri Palek and Songyong Liu and S. Chien},
  journal={Blood},
  year={1989},
  volume={73 2},
  pages={592-5}
}
The viscoelastic properties of the RBC membrane are in part determined by a submembrane network of proteins consisting of spectrin alpha beta heterodimers (SpD) assembled head-to-head to form spectrin tetramers (SpT) and spectrin oligomers (SpO). SpT, in turn, are connected into a two-dimensional network by the linkage of distal ends of SpT to protein 4.1 and actin. With the micropipette technique, we determined the membrane viscoelastic properties of RBCs from a subset of patients with… CONTINUE READING

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