Visceral leishmaniasis: a difficult diagnosis and unusual causative agent.

  title={Visceral leishmaniasis: a difficult diagnosis and unusual causative agent.},
  author={Ran Oren and Lionel F. Schnur and Dina Ben Yehuda and V Mayner and Elimelech Okon and Eliezer A. Rachmilewitz},
  journal={The Journal of infectious diseases},
  volume={164 4},
In a young man who had a prolonged fever of unknown origin, hepatosplenomegaly, and progressive pancytopenia, stained smears, blood-agar cultures of bone marrow, and serologic testing for antileishmanial antibodies were negative. Biopsies from liver and bone marrow were uninformative. Visceral leishmaniasis was diagnosed only after splenectomy, when amastigotes were finally cultured from the spleen. The parasite was shown to be an unusual leishmanial parasite, possessing a mixture of intrinsic… CONTINUE READING


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