Visceral fat accumulation is an important determinant of PAI-1 levels in young, nonobese men and women: modulation by cross-sex hormone administration.

@article{Giltay1998VisceralFA,
  title={Visceral fat accumulation is an important determinant of PAI-1 levels in young, nonobese men and women: modulation by cross-sex hormone administration.},
  author={Erik J Giltay and Jolanda M H Elbers and Louis J Gooren and Jef J. Emeis and Teake Kooistra and Henk Asscheman and Coen D A Stehouwer},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={1998},
  volume={18 11},
  pages={1716-22}
}
Increased plasminogen activator inhibitor type-1 (PAI-1) levels, leading to impaired fibrinolysis, are associated with increased visceral fat in middle-aged and obese subjects. It is unknown, however, whether this association is independent of other disturbances clustered in the insulin resistance syndrome. We analyzed this association in young, nonobese… CONTINUE READING