Visceral and subcutaneous adiposity and brachial artery vasodilator function.

  title={Visceral and subcutaneous adiposity and brachial artery vasodilator function.},
  author={Nisha I. Parikh and Michelle J. Keyes and Martin G. Larson and Karla M. Pou and Naomi M. Hamburg and Joseph A. Vita and Christopher J. O'Donnell and Ramachandran S. Vasan and Gary F. Mitchell and Udo Hoffmann and Caroline Fox and Emelia J Benjamin},
  volume={17 11},
Endothelial dysfunction may link obesity to cardiovascular disease (CVD). We tested the hypothesis that visceral abdominal tissue (VAT) as compared with subcutaneous adipose tissue (SAT) is more related to endothelium-dependent vasodilation. Among Framingham Offspring and Third Generation cohorts (n = 3,020, mean age 50 years, 47% women), we used multivariable linear regression adjusted for CVD and its risk factors to relate computed tomography (CT)-assessed VAT and SAT, BMI, and waist… CONTINUE READING