Visceral adiposity in gastrointestinal and hepatic carcinogenesis.

@article{Vongsuvanh2013VisceralAI,
  title={Visceral adiposity in gastrointestinal and hepatic carcinogenesis.},
  author={Roslyn Vongsuvanh and Jacob George and Liang Qiao and David van der Poorten},
  journal={Cancer letters},
  year={2013},
  volume={330 1},
  pages={
          1-10
        }
}
There is emerging evidence that the association between obesity and cancer is mediated by visceral rather than generalised body fat. Visceral fat has been directly implicated in the risk and progression of several gastrointestinal cancers including colorectal, oesophageal, pancreatic and hepatocellular carcinomas. Excess visceral adipose tissue induces a state of chronic systemic inflammation and altered metabolic activity that promotes a pro-oncogenic environment. This review examines the… CONTINUE READING

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