Virus structures: Those magnificent molecular machines

  title={Virus structures: Those magnificent molecular machines},
  author={Dennis Henry Bamford},
  journal={Current Biology},
Double-stranded RNA viruses face two major problems: the endogenous machinery of its host cells does not replicate RNA genomes, and double-stranded RNA provokes strong cellular defence responses such as interferon induction and gene silencing. The solution for the virus is to keep the genomic double-stranded RNA always in a separate container, an icosahedral viral capsid, and to more-or-less autonomously replicate the genome with machinery built into this capsid. In most Reoviridae, this… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.


Publications referenced by this paper.
Showing 1-10 of 11 references

Principles of virion structure, function, and assembly

  • S Casjens
  • 2000
1 Excerpt

Similar Papers

Loading similar papers…