Virus-specific T cell responses in macaques acutely infected with SHIV(sf162p3).

  title={Virus-specific T cell responses in macaques acutely infected with SHIV(sf162p3).},
  author={Bapi Pahar and Xiaolei Wang and Jason Dufour and Andrew A Lackner and Ronald S Veazey},
  volume={363 1},
CD4(+) T helper and CD8(+) cytotoxic T lymphocyte responses are believed to play an important role in the control of primary HIV and SIV infection. However, the role of these cells in macaques acutely infected with SHIV(sf162p3) has not been well characterized. In this study, ten adult rhesus macaques were intravaginally infected with SHIV(sf162p3), and antigen-specific cytokine responses to SHIV-Tat, Nef, Gag and Env peptide pools were examined through 70 days post inoculation (p.i.) using… CONTINUE READING

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