Virus-like particles: flexible platforms for vaccine development.

@article{Chackerian2007ViruslikePF,
  title={Virus-like particles: flexible platforms for vaccine development.},
  author={Bryce Chackerian},
  journal={Expert review of vaccines},
  year={2007},
  volume={6 3},
  pages={
          381-90
        }
}
  • Bryce Chackerian
  • Published in Expert review of vaccines 2007
  • Biology, Medicine
  • Virus-like particles (VLPs) consist of viral structural proteins that, when overexpressed, spontaneously self-assemble into particles that are antigenically indistinguishable from infectious virus or subviral particles. VLPs can be considered as dense, repetitive arrays of one or more protein subunits with properties that are highly advantageous for use as stand-alone vaccines or as vaccine platforms. This review discusses the development of VLP-based platform technologies for vaccines against… CONTINUE READING

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