Virus-like Particles and E1AE4 Protein Expressed from the Human Papillomavirus Type 11 Bicistronic E1AE4AL1 Transcript

@article{Brown1996ViruslikePA,
  title={Virus-like Particles and E1AE4 Protein Expressed from the Human Papillomavirus Type 11 Bicistronic E1AE4AL1 Transcript},
  author={Michael Brown and Pratt and Bryan and Fife and G Jansen},
  journal={Virology},
  year={1996},
  volume={222 1},
  pages={43-50}
}
Detection of E1AE4 protein in human papillomavirus (HPV 11)-infected tissue is tightly linked to detection of L1 major capsid protein. The only L1-containing transcript identified in HPV 11-infected tissue is the bicistronic E1AE4AL1 mRNA, potentially encoding both the E1AE4 and the L1 proteins. It has not been established that these proteins can be expressed from the E1AE4AL1 transcript. The HPV 11 E1AE4AL1 sequence was cloned by reverse transcriptase polymerase chain reaction into the p1393… CONTINUE READING