Virus-induced non-specific signals cause cell cycle progression of primed CD8(+) T cells but do not induce cell differentiation.

@article{Andreasen1999VirusinducedNS,
  title={Virus-induced non-specific signals cause cell cycle progression of primed CD8(+) T cells but do not induce cell differentiation.},
  author={Steven Andreasen and Jan Pravsgaard Christensen and Ole Marker and Allan Randrup Thomsen},
  journal={International immunology},
  year={1999},
  volume={11 9},
  pages={1463-73}
}
In this report the significance of virus-induced non-specific T cell activation was re-evaluated using transgenic mice in which about half of the CD8(+) T cells expressed a TCR specific for amino acids 33-41 of lymphocytic choriomeningitis virus glycoprotein I. This allowed tracing of cells with known specificity and priming history in an environment also containing a normal heterogeneous CD8(+) population which served as an intrinsic control. Three parameters of T cell activation were analyzed… CONTINUE READING
14 Citations
41 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 41 references

interferon in virus-induced lymphopenia

  • C. Tanchot, B. Rocha
  • Cell. Immunol
  • 1998

Similar Papers

Loading similar papers…