Virus-immune cytotoxic T-cell activity following negative selection of alloreactive precursor lymphocytes.

Abstract

Results obtained using negative selection protocols indicate that it is possible to obtain vaccinia-virus-specific killing of cells expressing H-2 types other than those encountered during physiologic development in thymus. This response has been found to be neither reciprocal for different H-2 types, nor identical for influenza and vaccinia viruses. Prior priming with virus apparently suppresses the capacity of T cells to be sensitized to H-2-different virus-infected cells.

Cite this paper

@article{Bennink1980VirusimmuneCT, title={Virus-immune cytotoxic T-cell activity following negative selection of alloreactive precursor lymphocytes.}, author={Jack R.. Bennink and Peter Doherty}, journal={Transplantation proceedings}, year={1980}, volume={12 1}, pages={172-4} }