Virulence test using nematodes to prescreen Nocardia species capable of inducing neurodegeneration and behavioral disorders

Abstract

BACKGROUND Parkinson's disease (PD) is a disorder characterized by dopaminergic neuron programmed cell death. The etiology of PD remains uncertain-some cases are due to selected genes associated with familial heredity, others are due to environmental exposure to toxic components, but over 90% of cases have a sporadic origin. Nocardia are Actinobacteria that… (More)
DOI: 10.7717/peerj.3823

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