Virulence studies of Scedosporium and Fusarium species in Drosophila melanogaster.

  title={Virulence studies of Scedosporium and Fusarium species in Drosophila melanogaster.},
  author={Gregory A Lamaris and Georgios Chamilos and Russell E Lewis and Dimitrios P Kontoyiannis},
  journal={The Journal of infectious diseases},
  volume={196 12},
We developed a model of infection, using 1 Fusarium species (F. moniliforme) and 2 Scedosporium species (S. apiospermum and S. prolificans), in wild-type and Toll-deficient Drosophila melanogaster flies by injecting them with a standardized conidia inoculum. Wild-type flies were resistant to infection with both S. apiospermum and S. prolificans but were susceptible to infection with F. moniliforme. When Toll-deficient flies were infected with any of the 3 pathogens, the result was acute… CONTINUE READING
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