Virulence plasmid harbored by uropathogenic Escherichia coli functions in acute stages of pathogenesis.

@article{Cusumano2010VirulencePH,
  title={Virulence plasmid harbored by uropathogenic Escherichia coli functions in acute stages of pathogenesis.},
  author={Corinne K Cusumano and Chia S. Hung and Swaine L Chen and Scott J Hultgren},
  journal={Infection and immunity},
  year={2010},
  volume={78 4},
  pages={1457-67}
}
Urinary tract infections (UTIs), the majority of which are caused by uropathogenic Escherichia coli (UPEC), afflict nearly 60% of women within their lifetimes. Studies in mice and humans have revealed that UPEC strains undergo a complex pathogenesis cycle that involves both the formation of intracellular bacterial communities (IBC) and the colonization of extracellular niches. Despite the commonality of the UPEC pathogenesis cycle, no specific urovirulence genetic profile has been determined… CONTINUE READING

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