Virulence of pPst+ and pPst- strains of Yersinia pestis for guinea-pigs.

@article{Samoilova1996VirulenceOP,
  title={Virulence of pPst+ and pPst- strains of Yersinia pestis for guinea-pigs.},
  author={S V Samoilova and L V Samoĭlova and I N Yezhov and Ilya G. Drozdov and Andrey P Anisimov},
  journal={Journal of medical microbiology},
  year={1996},
  volume={45 6},
  pages={440-4}
}
Guinea-pigs were infected subcutaneously or by respiratory challenge with plasmid-containing (pPst+pCad+pFra+) Yersinia pestis strain 358 and its pPst-pCad+pFra+, pPst+pCad+pFra- and pPst-pCad+pFra- derivatives, grown in vitro at 28 degrees C or at 37 degrees C. Lack of plasmid pPst did not lead to an increase in LD50 with either route of challenge. When the virulence of the four Y. pestis strains grown at the two temperatures was compared, the LD50 values of those grown at 37 degrees C were… CONTINUE READING

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