Virulence of Sporothrix schenckii conidia and yeast cells, and their susceptibility to nitric oxide.

@article{Fernandes2000VirulenceOS,
  title={Virulence of Sporothrix schenckii conidia and yeast cells, and their susceptibility to nitric oxide.},
  author={Karla Simone da Silva Fernandes and Ana Lucia Coelho and Leila Maria Lopes Bezerra and Christina Barja-Fidalgo},
  journal={Immunology},
  year={2000},
  volume={101 4},
  pages={563-9}
}
The involvement of nitric oxide (NO) in macrophage (M phi) fungicidal activity against Sporothrix schenckii, and the relationship between NO susceptibility and the differential virulence of conidia and yeast cells, were investigated. Confirming a previously reported correlation between the length of time in culture and virulence of S. schenckii, conidia isolated from 12-day mycelial cultures (Ss-12) were less virulent to mice than conidia from 7-day cultures (Ss-7) or yeast cells. Indicative of… CONTINUE READING

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