Virulence in Trypanosoma cruzi infection correlates with the expression of a distinct family of sialidase superfamily genes.

@article{Weston1999VirulenceIT,
  title={Virulence in Trypanosoma cruzi infection correlates with the expression of a distinct family of sialidase superfamily genes.},
  author={Donald Weston and Bhavita Patel and Wesley C E Van Voorhis},
  journal={Molecular and biochemical parasitology},
  year={1999},
  volume={98 1},
  pages={105-16}
}
The overall success of Trypanosoma cruzi depends on its ability to invade the host and establish a long-term infection. Little is known of the genetic factors responsible for observed differences in virulence from strain to strain in T. cruzi. A virulent T. cruzi line was derived from an attenuated parental line by two passages through mice. To identify… CONTINUE READING