Virulence determinants between New York 99 and Kunjin strains of West Nile virus.

@article{Audsley2011VirulenceDB,
  title={Virulence determinants between New York 99 and Kunjin strains of West Nile virus.},
  author={Michelle Audsley and Judith H. Edmonds and Wenjun Liu and Vlad V Mokhonov and Ekaterina I. Mokhonova and Ezequeil Balmori Melian and Natalie A. Prow and Roy A Hall and Alexander A Khromykh},
  journal={Virology},
  year={2011},
  volume={414 1},
  pages={
          63-73
        }
}
An attenuated Australian strain of West Nile virus (WNV), Kunjin (KUN), shares ~98% amino acid homology with the pathogenic New York 99 NY99 strain (NY99). To investigate the viral factors involved in NY99 virulence we generated an infectious cDNA clone of the WNV NY99 4132 isolate from which virus was recovered and was shown to be indistinguishable from the parental isolate. We then introduced the regions of the NY99 non-structural (NS) proteins and/or untranslated regions (UTRs) into the KUN… CONTINUE READING
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The ecology and epidemiology of Kunjin virus

R. A. Hall, A. K. Broom, D. W. Smith, J. S. Mackenzie
  • Curr. Top. Microbiol. Immunol
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