Virucidal effect of peppermint oil on the enveloped viruses herpes simplex virus type 1 and type 2 in vitro.

  title={Virucidal effect of peppermint oil on the enveloped viruses herpes simplex virus type 1 and type 2 in vitro.},
  author={Andrea E. Schuhmacher and Jürgen Reichling and Paul Schnitzler},
  journal={Phytomedicine : international journal of phytotherapy and phytopharmacology},
  volume={10 6-7},
The virucidal effect of peppermint oil, the essential oil of Mentha piperita, against herpes simplex virus was examined. [] Key Method The inhibitory activity against herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2) was tested in vitro on RC-37 cells using a plaque reduction assay. The 50% inhibitory concentration (IC50) of peppermint oil for herpes simplex virus plaque formation was determined at 0.002% and 0.0008% for HSV-1 and HSV-2, respectively. Peppermint oil exhibited high…

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