Virtual Screening for High Specificity Inhibitors of SSH-2 Against Dual Specificity Phosphatases of Similar Homology

Abstract

Dual Specificity Phosphatases (DSPs) are a subject of interest because of their ability as a protein tyrosine phosphatase group that can dephosphorylate phospho-tyrosine and phospho-serine/threonine. While relatively little is understood about them, their regulatory balance has been linked to the development of cancers, Alzheimer's disease, diabetes, and… (More)

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