Virological effects and safety of combined double filtration plasmapheresis (DFPP) and interferon therapy in patients with chronic hepatitis C: A preliminary study.

@article{Yamashita2006VirologicalEA,
  title={Virological effects and safety of combined double filtration plasmapheresis (DFPP) and interferon therapy in patients with chronic hepatitis C: A preliminary study.},
  author={Tatsuya Yamashita and Kuniaki Arai and Akito Sakai and Eishiro Mizukoshi and Yoshio Sakai and Takashi Kagaya and Yasunari Nakamoto and Masao Honda and Takashi Wada and Hitoshi Yokoyama and Shuichi Kaneko},
  journal={Hepatology research : the official journal of the Japan Society of Hepatology},
  year={2006},
  volume={36 3},
  pages={167-75}
}
PURPOSE In patients with chronic genotype 1b hepatitis C and a high viral load, the viral load was reduced by double filtration plasmapheresis (DFPP), followed by combined interferon and ribavirin therapy. The safety and virological effects of this treatment method were preliminarily investigated. METHODS In nine patients with chronic hepatitis C, DFPP was performed three times on days 1, 2, and 4, and the administration of interferon and ribavirin was initiated immediately after DFPP on day… CONTINUE READING

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