Virological characterization of the hepatitis C virus JFH-1 strain in lymphocytic cell lines.


While hepatocytes are the major site of hepatitis C virus (HCV) infection, a number of studies have suggested that HCV can replicate in lymphocytes. However, in vitro culture systems to investigate replication of HCV in lymphocytic cells are severely limited. Robust HCV culture systems have been established using the HCV JFH-1 strain and Huh-7 cells. To… (More)
DOI: 10.1099/vir.0.83618-0

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