Virologic failure and second-line antiretroviral therapy in children in South Africa--the IeDEA Southern Africa collaboration.

@article{Davies2011VirologicFA,
  title={Virologic failure and second-line antiretroviral therapy in children in South Africa--the IeDEA Southern Africa collaboration.},
  author={Mary-Ann Davies and Harry Moultrie and Brian Eley and Helena Rabie and Gilles van Cutsem and Janet Giddy and Robin Wood and Karl Technau and O Keiser and Matthias Egger and Andrew Boulle},
  journal={Journal of acquired immune deficiency syndromes},
  year={2011},
  volume={56 3},
  pages={270-8}
}
BACKGROUND With expanding pediatric antiretroviral therapy (ART) access, children will begin to experience treatment failure and require second-line therapy. We evaluated the probability and determinants of virologic failure and switching in children in South Africa. METHODS Pooled analysis of routine individual data from children who initiated ART in 7 South African treatment programs with 6-monthly viral load and CD4 monitoring produced Kaplan-Meier estimates of probability of virologic… CONTINUE READING

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Sustained viremia is common among HIV - infected Ugandan children receiving antiretroviral therapy and not detected by WHO CD 4 criteria

TD Ruel, J Achan, E Charlebois
J Antimicrob Chemother • 2010

Sustained viremia is common among HIV-infected Ugandan children receiving antiretroviral therapy and not detected by WHO CD4

TD. Ruel, J. Achan, E Charlebois
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