Virologic Failure and Second-Line Antiretroviral Therapy in Children in South Africa—The IeDEA Southern Africa Collaboration

@article{Davies2011VirologicFA,
  title={Virologic Failure and Second-Line Antiretroviral Therapy in Children in South Africa—The IeDEA Southern Africa Collaboration},
  author={M. Davies and H. Moultrie and B. Eley and H. Rabie and G. van Cutsem and J. Giddy and R. Wood and Karl Technau and O. Keiser and M. Egger and A. Boulle},
  journal={JAIDS Journal of Acquired Immune Deficiency Syndromes},
  year={2011},
  volume={56},
  pages={270-278}
}
  • M. Davies, H. Moultrie, +8 authors A. Boulle
  • Published 2011
  • Medicine
  • JAIDS Journal of Acquired Immune Deficiency Syndromes
  • Background: With expanding pediatric antiretroviral therapy (ART) access, children will begin to experience treatment failure and require second-line therapy. We evaluated the probability and determinants of virologic failure and switching in children in South Africa. Methods: Pooled analysis of routine individual data from children who initiated ART in 7 South African treatment programs with 6-monthly viral load and CD4 monitoring produced Kaplan-Meier estimates of probability of virologic… CONTINUE READING

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 63 REFERENCES
    Predictors of Long-Term Viral Failure Among Ugandan Children and Adults Treated With Antiretroviral Therapy
    • 212
    Antiretroviral treatment for children with peripartum nevirapine exposure.
    • 145