Virologic, immunologic, and clinical benefits from early combined antiretroviral therapy in infants with perinatal HIV-1 infection.

@article{Chiappini2006VirologicIA,
  title={Virologic, immunologic, and clinical benefits from early combined antiretroviral therapy in infants with perinatal HIV-1 infection.},
  author={Elena Chiappini and L Galli and P. -A. Tovo and Clara Gabiano and Guido Castelli Gattinara and Alfredo Guarino and Raffaele Badolato and Carlo Giaquinto and Catiuscia Lisi and Maurizio de Martino},
  journal={AIDS},
  year={2006},
  volume={20 2},
  pages={207-15}
}
OBJECTIVE To investigate the impact of early versus deferred combined antiretroviral treatment (ART) in asymptomatic or moderately symptomatic [Centers for Disease Control and Prevention (CDC) category N, A or B] infants with perinatal HIV-1 infection. METHODS A multi-centre nationwide case-control study was conducted. Data from 30 infants treated with combined ART with three or more drugs before 6 months of age were compared with data from 103 infants starting ART with three or more drugs… CONTINUE READING
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