Viral vector targeting.

  title={Viral vector targeting.},
  author={K W Peng and Stephen Russell},
  journal={Current opinion in biotechnology},
  volume={10 5},
The field of viral vector targeting is advancing rapidly. Recent advances include the successful use of bifunctional crosslinkers to target adenoviral and retroviral vectors, elucidation of the crystal structures of an adenoviral and a retroviral receptor-binding domain, and definition of strategies for inserting short targeting peptides and larger polypeptide-binding domains into the coat proteins of a number of different viral vectors. Novel targeting strategies based on host range… CONTINUE READING


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